Multiple Sclerosis

Affecting an estimated 2.5 million people worldwide, multiple sclerosis (MS) is the most common neurological cause of debilitation in young adults. Incurable, and with the precise causes still unknown, both diagnosis and management of the condition is complicated. This book summarizes the latest understanding of the causes of the disease, using accessible, bullet-point text to describe key clinical features and diagnostic criteria. Disease-modifying therapies and management of symptoms, including fatigue, tremor and cognitive changes, are covered in detail. With a chapter focusing solely on presentations in the emergency room, the importance of recognizing these neurological emergencies is emphasised, along with indications for admission in MS patients. The impact of MS on women's reproductive health and the increasing recognition of MS in pediatric patients is also explored. An up-to-date and practical approach to the accurate diagnosis and management of MS, this is an invaluable resource for both hospital and outpatient settings.

    Bullet points make text accessible for busy clinicians diagnosing patients in hospital settings, essential in emergency presentations
    Provides a detailed and comprehensive approach to the differential diagnosis of multiple sclerosis and mimics of the condition, crucial for giving patients the personalised care they need
    Clinical pearls from the authors offer the insight of many years' experience treating patients with multiple sclerosis

Contents

1. Autoimmune CNS Emergencies
2. Clinical Features of MS
3. MS Phenotypes
4. Diagnostic Evaluation
5. Differential Diagnosis
6. Neuroimaging in Multiple Sclerosis and its Mimics
7. Disease-Modifying Therapies (DMT's)
8. Treatment Goals
9. Symptomatic Management
10. Reproductive Issues
11. Pediatric MS
12. Useful Websites
Appendix.

Carlos A. Pérez is a Multiple Sclerosis and Neuroimmunology clinical and research fellow at the University of Texas Health Science Center, Houston, TX, USA.

Andrew Smith is a Staff Neurologist at OhioHealth Multiple Sclerosis Center at OhioHealth Riverside Methodist Hospital in Columbus, Ohio, USA.

Flavia Nelson is a Professor of Neurology and the Director of the Multiple Sclerosis Division at the University of Minnesota, Minneapolis, MN, USA.