Treatment of Primary Glomerulonephritis

Primary glomerulonephritis is one of the most frequent renal diseases, and a main cause of end-stage kidney disease. Glomerulonephritis has multiple subtypes, each with different physiopathologies, clinical presentations, and management requirements, which makes treatment difficult. As a complex set of diseases, the choice of symptomatic and specific treatment is critical to ameliorating the relentless course of glomerulonephritis.

Focusing on all aspects of primary glomerulonephritis, from their epidemiologies and classification, to their pathogenesis and treatment, this third edition of Treatment of Primary Glomerulonephritis has been fully updated to include the latest research and evidence-based practice. With a strong emphasis on drugs used for both symptomatic and specific treatments, mechanisms of action, effectiveness, and potential toxicity are considered for therapeutic strategies in the different subtypes of primary glomerulonephritis.

Each chapter follows a clear and logical format, allowing easy access to key information. Featuring over 20 full-colour histological images of different diseases to aid diagnosis, and with commentary from internationally recognised experts in the field, this new edition is an essential resource for all practising or academic clinical nephrologists.

Table of Contents

1: A definition, modern classification, and global epidemiology of primary glomerulonephritis, Claudio Ponticelli and Richard Glassock
2: Symptomatic therapy, Richard Glassock
3: The pharmacology of old and new agents for specific therapy of primary glomerular diseases, Claudio Ponticelli and Richard Glassock
4: Minimal change disease, Claudio Ponticelli, Richard Glassock, and Rosanna Coppo
5: Focal and segmental glomerular sclerosis, Claudio Ponticelli, Richard Glassock, and Francesco Scolari
6: Membranous nephropathy, Claudio Ponticelli, Richard Glassock, and Patrizia Passerini
7: Immunoglobulin A nephropathy, Richard Glassock, Claudio Ponticelli, and Kar Neng Lai
8: Infection-related and renal-limited glomerulonephritis, Richard Glassock, Lee Hebert, Gabriella Moroni, and Claudio Ponticelli
9: C3 Glomerulopathies and 'idiopathic' immune complex membranoproliferative glomerulonephritis, Richard Glassock and Fernando C. Fervenza
10: Renal-limited vasculitis, Richard Glassock and Patrick Nachman
11: Other primary glomerular diseases, Claudio Ponticelli and Gabriella Moroni