Oxford Specialist Handbook: Myeloproliferative Neoplasms

Our understanding of myeloproliferative neoplasms (MPN) disorders, a group of clonal haematological malignancies characterized by excessive accumulation of one or more myeloid cell lineages, has grown considerably over the past four decades.

Myeloproliferative Neoplasms offers a detailed evidence-based guide to MPNs in an easily accessible format, structured to facilitate learning specialist information by presenting core information in 'bite size' chunks.

Each chapter summarises the state-of-the art preclinical and clinical knowledge, and its impact on the clinical management of patients with MPNs. This practical guide, written by experts in the field, is essential reading for oncologists, haematologists, and other health care professionals interested in the field of MPNs.

Table of Contents

1: History of the myeloproliferative neoplasms, Tariq I. Mughal and Tiziano Barbui
2: Genomic landscape of myeloproliferative neo-plasms, Srinivas K. Tantravahi, Jamshid S. Khorashad, and Michael W.Deininger
3: Pathogenesis of myeloproliferative neoplasms, Angela G. Fleischman and Richard A. Van Etten
4: Haematopathology of myeloproliferative neoplasms, Hans Michael Kvasnicka and Jüergen Thiele
5: Prognostic factors of chronic myeloid leukaemia, Michele Baccarani, Fausto Castagnetti, Gabriele Gugliotta, Francesca Palandri, Simona Soverini, and Gianantonio Rosti
6: Molecular risk stratification of Myeloproliferative Neoplasms, Paola Guglielmelli and Alessandro M. Vannucchi
7: Chronic myeloid leukaemia, Tariq I. Mughal
8: Polycythaemia vera, Tiziano Barbui and Guido Finazzi
9: Myelofibrosis, Claire Harrison, Yan Beauverd, and Donal McLorran
10: Essential thrombocythemia, Carlos Besses, Beatriz Bellosillo, and Alberto Alvarez-Larrán
11: Systemic mastocytosis, Jason Gotlib
12: Myelodysplastic syndromes/myeloproliferative neoplasms, Eric Padron, David Sallman, Tariq I. Mughal, and Alan F. List
13: Eosinophilia-associated myeloproliferative neoplasms, Andreas Reiter and Nicholas C. P. Cross
14: Transformation of myeloproliferative neoplasms to acute leukaemia, Omar Abdelwahab, Raajit Rampal, Catriona Jamieson, and Tariq I. Mughal
15: Monitoring efforts in myeloproliferative neoplasms, Daniel Egan and Jerald P. Radich
16: Stem cell transplantation for BCR-ABL1-postive and negative myeloproliferative neoplasms, Alessandro Rambaldi and Nicholas Kröger
17: Assessment of disease burden in patients with myeloproliferative neoplasms, Holly L. Geyer, Deepti Radia, Nicholas Sarlis, and Ruben A. Mesa
18: Clinical trials in bcr-abl1-negative myeloproliferative neo-plasms, Giovanni Barosi and Gianni Tognoni