Advanced Therapy in Epilepsy

A comprehensive and up-to-date primer on the latest therapeutic advances in the management and treatment of epilepsy. This Includes practical information on diagnostic criteria for all different syndromes along with detailed discussions of appropriate agents. About the Authors James W. Wheless, MD Professor and Chair of Pediatric Neurology LeBonheur Chair in Pediatric Neurology University of Tennessee Health Science Center Memphis, Tennessee James Willmore, MD Associate Dean and Professor of Neurology Saint Louis University School of Medicine St. Louis, Missouri Roger A. Brumback, MD Professor of Psychiatry and Pathology Chairman, Department of Pathology Creighton University Medical Center Omaha, Nebraska Table of Contents Chapter 1: Introduction Chapter 2: Epilepsy: Brief Historical Perspective Chapter 3: Definitions and Classification of Epilepsy and Seizures Chapter 4: Neurophysiologic Basis of Epileptiform Activity Chapter 5: Epidemiology Chapter 6: Magnetoencephalography in the Diagnosis and Treatment of Epilepsy Chapter 7: Clinical Neurophysiology III: Other Techniques Chapter 8: Neuroimaging in Epilepsy Chapter 9: Experimental Models of Seizures and Epilepsy Chapter 10: The EEG of Epilepsy Chapter 11: Genetic and Chromosomal Disorders in Epilepsy Chapter 12: Neuropathology of Pediatric Cerebral Resections for Epilepsy Chapter 13: Neurometabolic Disorders and Epilepsy Chapter 14: Neurocutaneous Disorders and Epilepsy Chapter 15: Neonatal Seizures Chapter 16: Epilepsy in Developmental Disorders Chapter 17: Epilepsy in Neurodegenerative Diseases Chapter 18: Acquired Lesions and Epilepsy Chapter 19: Febrile Seizures Chapter 20: Convulsive Status Epilepticus Chapter 21: Clinical Features, Diagnosis, and Treatment of Nonconvulsive Status Epilepticus Chapter 22: Temporal Lobe Epilepsy Syndromes Chapter 23: Partial-Onset Seizures and Localization-Related Epilepsy Syndromes Chapter 24: Generalized Seizures and Generalized Epilepsy Syndromes Chapter 25: Landau-Kleffner Syndrome and Language Dysfunction in Epilepsy Chapter 26: Rasmussen Encephalitis Chapter 27: Nonepileptic Paroxysmal Disorders Chapter 28: Psychogenic Nonepileptic Seizures Chapter 29: Neurotransmitters and Drug Development in Epilepsy Chapter 30: Antiepileptic Drugs: An Overview Chapter 31: Principles of Pharmacokinetics and Pharmacogenetics of Anticonvulsants Chapter 32: Pregnancy, Epilepsy, and Drug Treatment Chapter 33: Epileptic Drug Treatment in Special Populations Chapter 34: Systemic Metabolic Consequences of Antiepileptic Medication Chapter 35: Barbiturates Chapter 36: Benzodiazepines Chapter 37: Carbamazepine and Oxcarbazepine Chapter 38: Ethosuximide Chapter 39: Gabapentin and Pregabalin Chapter 40: Lamotrigine Chapter 41: Levetiracetam Chapter 42: Phenytoin and Fosphenytoin Chapter 43: Topiramate Chapter 44: Valproic Acid Chapter 45: Vigabatrin Chapter 46: Zonisamide Chapter 47: Other Antiepileptic Drugs Chapter 48: Use of Antidepressants in Epilepsy:What All Neurologists Should Know Chapter 49: Immunotherapy in Epilepsy Chapter 50: Dietary Therapy for Epilepsy Chapter 51: Neurostimulation Therapy for Epilepsy Chapter 52: Epilepsy Surgery Chapter 53: Prognosis and Ongoing Management of Epilepsy Chapter 54: Neuropsychiatric Comorbidities with Epilepsy in Children and Adolescents Chapter 55: Epilepsy and Cognition Chapter 56: Practical Treatment Strategies of Psychiatric Comorbidities in Adults with Epilepsy Chapter 57: Therapeutic Uses of Seizures in Neuropsychiatry Chapter 58: Social Challenges Among Children and Adolescents with Intractable Epilepsy Chapter 59: Monitoring for Adverse Effects of Antiepileptic Drugs