Lennette's Laboratory Diagnosis of Viral Infections

Written from the viewpoint of the diagnostician, this Fourth Edition of Laboratory Diagnosis of Viral Infections explores all human viral diseases and the molecular techniques usedd to detect and manage these diseases. This case-based and example-driven text provides extensive information on molecular detection of viruses and the design and validation of molecular assays. Key features include: • new chapter on viral pathogens • more illustrations, tables, and algorithms • updates on emerging viruses, such as avian influenza, West Nile Virus, hemorrhagic fever virus, human metapneumovirus, and bocavirus • highlights of specific viruses that reflect the current dependence on molecular techniques • the costs and benefits of molecular vs. classical techniques • coverage of unbiased chip or multiplex-based assays • the increased role of the diagnostic virology laboratory in the management and detection of viral infections Keith R. Jerome (University of Washington, Seattle, WA, USA) CONTENTS OF THE PREVIOUS EDITION: Overview: clinical virology - concepts and perspectives; surgical pathology and diagnostic cytology of viral infections; electron microscopy of viral infections; diagnosis by antigen detection; nucleic acid detection; applications of molecular amplification methods in diagnostic virology; application of genetically engineered cell lines to diagnostic virology; detection methods for nucleic acid amplification products; serologic tests in clinical virology; flow cytometry in viral diagnosis; assessment of a viral diagnosis test; virus isolation versus molecular methods; antiviral therapy. Specific viral infections: adenoviruses; arboviruses; arenaviruses and filoviruses; human cytomegalovirus; enteroviruses; Epstein-Barr virus; gastroenteritis viruses; hantavirus pulmonary syndrome; parenterally transmitted hepatitis viruses; the enterically transmitted hepatitis viruses; herpes simplex viruses types 1 and 2; human herpes virus 6, human herpes virus 7, and human herpes virus 8; human immunodeficiency viruses - HIV-1 and HIV-2; human t-lymphotropic viruses types I and II; influenza virus; measles (rubeola) virus; mumps virus; human papillomaviruses; human parainfluenza viruses; human parvovirus B19; polyomaviruses BK and JC; human poxviruses; rabies virus; respiratory syncytial virus; rhinoviruses; rubella virus; varicella zoster infections.