Postgraduate Haematology provides up–to–date knowledge of the pathogenesis, clinical and laboratory features, management and treatment of a wide range of blood and bone marrow disorders in a concise and user friendly style.
Up–to–date knowledge of the pathogenesis, clinical and laboratory features and management of all blood disorders
New sections reflect advances in the specialty, e.g. knowledge gained from new generation sequencing, latest anticoagulant drugs, diagnostic laboratory tools, and treatment strategies
Superb four–color illustrations and photomicrographs of blood cells and tissues throughout
Includes algorithms to aid with decision–making for treatment
Companion website incorporating interactive MCQs to aid with exam preparation, figures for download and full chapters
Contents
1 Stem cells and haemopoiesis
Emma de Pater, Elaine Dzierzak
2 Erythropoiesis
Douglas R. Higgs, Noémi Roy, Deborah Hay
3 Iron metabolism, iron deficiency and disorders of the haem synthesis
Clara Camaschella, A. Victor Hoffbrand, Chaim Hershko
4 Iron overload
Clara Camaschella, A. Victor Hoffbrand, Maria Domenica Cappellini
5 Megaloblastic anaemia
A. Victor Hoffbrand
6 Haemoglobin and the inherited disorders of globin synthesis
Swee Lay Thein, David Rees
7 Sickle cell disease
Anne Marsh, Elliott P Vichinsky
8 Hereditary disorders of the red cell membrane and disorders of red cell metabolism
Paola Bianchi, Narla Mohandas
9 Acquired haemolytic anaemias
Modupe O. Elebute, Rachel Kesse–Adu
10 Inherited aplastic anaemia/bone marrow failure syndromes
Inderjeet S. Dokal
11 Acquired aplastic anaemia and paroxysmal nocturnal haemoglobinuria
Judith C.W. Marsh, Austin Kulasekararaj, Neal S. Young, Peter Hillmen
12 Red cell immunohaematology
Marcela Contreras, Geoff Daniels, Shubha Allard
13 Clinical blood transfusion
Shubha Allard, Marcela Contreras
14 Phagocytes
John Mascarenhas, Marina Kremyanskaya, Ronald Hoffman
15 Lysosomal storage disorders
Atul B Mehta, Derralynn A Hughes
16 Normal lymphocytes and non–neoplastic lymphocyte disorders
Paul Moss, Mark Drayson
17 The spleen
Paul Moss
18 The molecular basis of haematological malignancies
Niccolo Bolli, George Vassiliou
19 Laboratory diagnosis of haematological neoplasms
Torsten Haferlach, Barbara J. Bain
20 Acute Myeloid Leukaemia
Alan K. Burnett, David Grimwade
21 Adult Acute Lymphoblastic leukaemia
Clare J. Rowntree, Adele K. Fielding
22 Childhood acute lymphoblastic leukaemia
Ajay Vora
23 Supportive care in the management of leukaemia
Eliza Gil, Vanya Gant, Panagiotis Kottaridis
24 Chronic Myeloid Leukaemia
David T O Yeung, Timothy P Hughes
25 The myelodysplastic syndromes
Kavita Raj, Ghulam J Mufti
26 Myeloproliferative neoplasms
Peter J Campbell, Claire Harrison, Anthony R Green
27 Chronic lymphocytic leukaemia and other chronic B–cell disorders
Emili Montserrat, Peter Hillmen
28 T–Cell Lymphoproliferative Disorders
Pier Luigi Zinzani, Alessandro Broccoli
29 Multiple myeloma
Jesús San–Miguel, Joan Bladé
30 Amyloidosis
Simon D.J. Gibbs, Philip N. Hawkins
31 The classification of lymphomas: updating the WHO classification
Elias Campo, Stefano A. Pileri
32 Classical Hodgkin Lymphoma
Piers Blombery, David Linch
33 Non–Hodgkin Lymphoma: Low Grade
William Townsend, Robert Marcus
34 Non–Hodgkin lymphoma: high grade
Jessica Okosun, Kate Cwynarski
35 Stem cell transplantation
Charles Craddock, Ronjon Chakraverty
36 Normal haemostasis
Keith Gomez, John H. McVey
37 The vascular function of platelets
Stephen P. Watson, Neil V. Morgan, Paul Harrison
38 Inherited bleeding disorders
Michael A. Laffan, K. John Pasi
39 Rare inherited coagulation disorders
Flora Peyvandi, Marzia Menegatti
40 Acquired coagulation disorders
Peter W. Collins, Jecko Thachil, Cheng–Hock Toh
41 Congenital Platelet Disorders
Maurizio Margaglione, Paul R.J. Ames
42 Primary immune thrombocytopenia
Drew Provan, Adrian C Newland
43 Thrombotic thrombocytopenic purpura and hemolytic uremic syndrome (congenital and acquired)
Pier Mannuccio Mannucci, Flora Peyvandi, Roberta Palla
44 Heritable thrombophilia
Trevor Baglin, David Keeling
45 Acquired venous thrombosis
Beverley J. Hunt, Henry Watson
46 Antithrombotic agents
Trevor Baglin, David Keeling
47 Management of VTE
Trevor Baglin, David Keeling
48Haematological aspects of systemic disease
A. Victor Hoffbrand, Atul B. Mehta
49 Haematological aspects of tropical diseases
Imelda Bates, Ivy Ekem
50 Neonatal haematology
Irene Roberts, Subarna Chakravorty
WHO Classification : Tumours of the Haematopoietic and Lymphoid Tissues (2008)
A. Victor Hoffbrand MA, DM, FRCP, FRCPath, FRCP (Edin), DSc, FMedSci
Emeritus Professor of Haematology at University College London, London, UK
Douglas R. Higgs MD, FRCP, FRS
Professor of Molecular Haematology & Director, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK
David Keeling
Consultant in Haemophilia and Thrombosis, Oxford Haemophilia and Thrombosis Centre, Oxford University Hospitals, Oxford, UK
Atul B. Mehta MA, MD, FRCP, FRC Path
Consultant Haematologist & Clinical Director, RFH Lysosomal Storage Disorders Unit, Royal Free Hospital, London, UK
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