Management of Hematologic Malignancies

Hematologic malignancies were the first human cancers to be studied in depth at the molecular level, and recent years have seen important advances in treatment. This comprehensive reference book covers the full range of hematologic malignancies, including all subtypes of leukemias, lymphomas, and plasma cell dyscrasias. Authored by internationally known experts, each chapter emphasizes diagnostic work-up, staging, and therapeutic approaches. Up-to-date hematopathology, treatment, and outcomes data are presented in a way which is directly applicable to patient care. Highly illustrated with color images, graphs, flowcharts and treatment algorithms, the book is perfect for quick clinical reference as well as providing detailed reference lists for further study. With its authoritative and practical focus and visually stimulating presentation, this is a key text for hematology and oncology fellows, physicians, oncology nurses, physician assistants and other healthcare workers in the field of oncology. Contents Preface; 1. Molecular pathology of leukemia Maher Albitar and Amber Donahue; 2. Management of acute myeloid leukemia Alan K. Burnett; 3. Treatment of acute lymphoblastic leukemia (ALL) in adults Ryan Mattison, Sarah Larson and Wendy Stock; 4. Chronic myeloid leukemia Jorge Cortes; 5. Chronic lymphosytic leukemia/small lymphocytic lymphoma Susan O'Brien; 6. Myelodysplastic syndromes (MDS) Hagop Kantarjian; 7. Hairy cell leukemia Darren S. Sigal and Alan Saven; 8. Acute promyelocytic leukemia Francesco Lo Coco; 9. Myeloproliferative neoplasms Ayalew Tefferi; 10. Monoclonal gammopathy of undetermined significance, smoldering multiple myeloma, and multiple myeloma S. Vincent Rajkumar and Suzanne R. Hayman; 11. Amyloidosis and other rare plasma cell dyscrasias Angela Dispenzieri and Suzanne R. Hayman; 12. Waldenstrom's macrogloblinemia/lymphoplasmacytic lymphoma Steven P. Treon and Giampaolo Merlini; 13. WHO classification of lymphomas William W. L. Choi and Wing C. Chan; 14. Molecular pathology of lymphoma David J. Good and Randy D. Gascoyne; 15. International staging and response criteria for lymphomas Bruce D. Cheson; 16. Treatment approach to diffuse large B-cell lymphomas Sonali M. Smith and Julie M. Vose; 17. Mantle cell lymphoma Andre Goy; 18. Follicular lymphomas Francisco J. Hernandez-Ilizaturri and Myron Czuczman; 19. Hodgkin lymphoma Andrew M. Evens and Sandra J. Horning; 20. Treatment approaches to malt/marginal zone lymphoma Stephanie A. Gregory and Parameswaran Venugopal; 21. Peripheral T-cell lymphomas Steven Horwitz; 22. Mycosis fungoides and Sezary syndrome Christine Querfeld and Steven T. Rosen; 23. Central nervous system lymphoma Elizabeth R. Gerstner and Tracy T. Batchelor; 24. AIDS-related lymphomas Lawrence Kaplan; 25. Lymphoblastic lymphoma John Sweetenham; 26. Burkitt's/Burkitt-like lymphoma Julie M. Vose; Index.